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Am J Trop Med Hyg ; 83(6): 1295-300, 2010 Dec.
Article in English | MEDLINE | ID: mdl-21118937

ABSTRACT

Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions.


Subject(s)
Antiprotozoal Agents/therapeutic use , Leishmania major , Leishmaniasis, Cutaneous/epidemiology , Phosphorylcholine/analogs & derivatives , Adult , Afghanistan/epidemiology , Cryotherapy , Humans , Leishmaniasis, Cutaneous/drug therapy , Leishmaniasis, Cutaneous/parasitology , Leishmaniasis, Cutaneous/prevention & control , Male , Military Personnel , Netherlands , Phosphorylcholine/therapeutic use , Time Factors
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